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The main difference is the price, Viagra tablets are more expensive as they are branded medication. Viagra and Sildenafil are both reliable, safe, and officially-approved medications. Sildenafil is what is known as a PDE5 inhibitor, a class of drug including the similar Tadalafil (Cialis), that causes blood vessels to expand and relax. For this reason, it was originally developed as a drug for cardiac conditions, including pulmonary arterial hypertension (PAH).

After taking a dose of Viagra, the drug’s level in your body will gradually decrease over a period of a few hours. You’ll have low levels of the drug in your body after about 4 hours. (And at this point, the drug won’t be working any longer.) But it can actually take about 24 hours for Viagra to be completely removed from your body. Even though Viagra keeps working in your body for several hours, your erection shouldn’t last this long. In fact, in rare cases, Viagra can cause priapism (a long-lasting and sometimes painful erection). Remember, you should not change your dosage of Viagra without your doctor’s recommendation.

The pharmacokinetics of sildenafil in patients with severely impaired hepatic function (Child-Pugh Class C) have not been studied. A starting dose of 25 mg should be considered in patients with any degree of hepatic impairment [see Dosage and Administration (2.5) and Clinical Pharmacology (12.3)]. Co-administration of ritonavir, a strong CYP3A4 inhibitor, greatly increased the systemic exposure of sildenafil (11-fold increase in AUC). It is therefore recommended not to exceed a maximum single dose of 25 mg of VIAGRA in a 48 hour period [see Dosage and Administration (2.4), Warnings and Precautions (5.6), Clinical Pharmacology (12.3)]. Use caution when co-administering alpha-blockers with VIAGRA because of potential additive blood pressure-lowering effects. Prolonged erection greater than 4 hours and priapism (painful erections greater than 6 hours in duration) have been reported infrequently since market approval of VIAGRA.

Use only the brand of this medicine that your doctor prescribed. If you or your child are taking sildenafil as a liquid, 1ml is usually the same as taking a 10mg tablet, but it's important to always check the medicine label. For erectile dysfunction, it's best to take sildenafil on an empty stomach. The dose can be increased to 100mg or decreased to 25mg depending on its effect.

Viagra is specifically designed for use in adult men with erectile dysfunction and should not be used by women. There are no approved formulations for women, and its safety and effectiveness in females have not been well-established. If you are breastfeeding or planning to breastfeed while taking Viagra 100mg tablet, it is crucial to discuss the situation with your healthcare provider. The dosage you’re taking doesn’t change how long the effects will last for and the treatment won’t affect how long you last in bed. It may be that your doctor initially prescribed you Sildenafil 100mg. Although it’s more common to start on the 50mg dosage and work up to 100mg if you have no success.

The concomitant administration of the protease inhibitor ritonavir substantially increases serum concentrations of sildenafil (11-fold increase in AUC). If VIAGRA is prescribed to patients taking ritonavir, caution should be used. Data from subjects exposed to high systemic levels of sildenafil are limited. Decreased blood pressure, syncope, and prolonged erection were reported in some healthy volunteers exposed to high doses of sildenafil (200–800 mg). Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). 25mg is slightly less effective than 50mg and 100mg, but has the lowest risk of side effects and interactions with other medications.

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Manufacture and sale of sildenafil citrate drugs is common in China, where Pfizer's patent claim is not widely enforced. Sildenafil protects cyclic guanosine monophosphate (cGMP) from degradation by cGMP-specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum. The pharmacokinetics of sildenafil in patients with severely impaired hepatic function have not been studied. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state.

Sildenafil 100 mg tablets can have serious side effects, which are more dangerous at higher doses. For help with erections, the recommended dose for adults ages 18 to 64 years old is 50 milligrams (mg). No, the dose of Viagra does not depend on a person’s body weight. The dosage of Viagra depends on a person’s age, their kidney and liver function, and the improvement of their erectile dysfunction.

Store Viagra in a cool, dry place as per instruction of the patient information leaflet. As with any form of medication, Viagra tablets have side effects. Heavy meals can reduce the absorption of Viagra into the bloodstream, reducing its effectiveness. You should aim to eat a light meal, preferably a few hours before taking Viagra, to maximise its effectiveness. Avoid foods high in fat or carbohydrate as they can slow down the rate of absorption of Viagra into your bloodstream. Viagra has a high success rate of around&nbsp