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But if you take it with a meal, the drug may take about an hour longer than usual to start working. This is especially the case if you eat a high fat meal, such as a cheeseburger with fries. Grapefruit juice can affect the levels of some medications in your body. But there’s not much evidence to show that the fruit or its juice can affect Viagra levels.

Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence). These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. Your doctor may start treatment with a lower dose of sildenafil to minimize your risk of low blood pressure.

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