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Each oral medicine for ED has a slightly different chemical makeup. These small differences affect the way each medication works, such as how quickly it takes effect and wears off, and the possible side effects. Your doctor or other health care professional can recommend one for you based on these factors, other health conditions you have and any other medicines you take.

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For most people, it’s recommended that you take Viagra as needed, about 1 hour before you plan to have sex. But Viagra can actually be taken anywhere from 30 minutes to 4 hours before sexual activity. You shouldn’t take Viagra if you’re taking the pulmonary arterial hypertension (PAH) drugs listed below. Taking Viagra with these medications can cause your blood pressure to drop too low. Low blood pressure from Viagra usually isn’t a problem for most people.

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