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Peak concentration in the blood is reached after two hours for tadalafil and about one hour for sildenafil. As such, we always suggest taking medication about an hour or two before sexual activity. The time it takes for the drug to function will vary between patients, so use prior experience as a guide.

The patient addressed both questions at the final visit for the last 4 weeks of the study. The possible categorical responses to these questions were (0) no attempted intercourse, (1) never or almost never, (2) a few times, (3) sometimes, (4) most times, and (5) almost always or always. Sexual function data were also recorded by patients in a daily diary. In addition, patients were asked a global efficacy question and an optional partner questionnaire was administered. Therefore, the use of such combinations is not recommended.

A dose of Viagra will completely leave your system within about 20 to 24 hours. A doctor may adjust someone’s dosage of Viagra based on their age and medical history. For example, men older than 65 or those with hepatic or renal impairment are typically given a starting dose of 25 mg. The standard dose of Viagra for ED is 50 mg taken as needed, about one hour before sexual activity. According to manufacturer instructions, Viagra should only be taken once per day on an as-needed basis unless otherwise advised by a doctor.

The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it